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languages : it - es - de - fr celecoxib brand names: celebrex, celebra generic celebrex 100mg / generic celebrex 200mg celecoxib (generic celebrex) is a nonsteroidal anti-inflammatory drug (nsaid). it functions by reducing hormones that cause swelling and discomfort in the physical body. celecoxib is utilized to treat inflammation or pain caused by many conditions such as arthritis. ankylosing spondylitis. and menstrual pain. celecoxib can be used to treat juvenile rheumatoid arthritis in children who are in least 2 years old. it is used in the treatment of hereditary polyps in the colon also. people who take non-steroidal anti-inflammatory drugs (nsaids) (apart from aspirin) such as celecoxib may have an increased risk of having a center assault or a stroke than individuals who usually do not take these medications. these events might happen without warning and could cause death. this risk might be higher for individuals who take nsaids for a long time. do not consider an nsaid such as for example celecoxib should you have lately had a heart attack, unless directed to take action by your physician. tell your doctor if you or anyone in your loved ones has or offers ever had heart disease, a coronary attack, or a stroke, if you smoke, and if you have or possess ever endured high cholesterol, high blood pressure, or diabetes. get crisis medical help immediately in the event that you experience the following symptoms: upper body discomfort, shortness of breath, weakness in a single part or side of the physical body, or slurred speech. celecoxib is used to relieve pain, tenderness, inflammation and stiffness caused by osteoarthritis (arthritis the effect of a breakdown of the lining of the joints), arthritis rheumatoid (arthritis due to swelling of the liner of the joints), and ankylosing spondylitis (arthritis that mainly affects the spine). additionally it is used to take care of juvenile rheumatoid arthritis (a kind of arthritis that impacts children) in children 24 months of age and older. celecoxib (celebrex) is also used to treat painful menstrual intervals and to relieve other styles of short-term pain including pain caused by injuries, surgery and various other dental or medical procedures, or medical ailments that last for a restricted time. celecoxib can be in a course of nsaids known as cox-2 inhibitors. it works by stopping the body's creation of a material that triggers pain and inflammation. celecoxib can be sometimes used with medical procedures and other treatments to reduce the amount of polyps (abnormal growths) in the colon (good sized intestine) and rectum in sufferers with familial adenomatous polyposis (a condition where hundreds or a large number of polyps type in the colon and cancer may develop). talk to your doctor about the dangers of using this medicine for your condition. this medication may be prescribed for other uses; ask your pharmacist or doctor for more information. this medication is a non-steroidal anti-inflammatory drug (nsaid), a cox-2 inhibitor specifically, which relieves pain and swelling (inflammation ). it is utilized to treat arthritis. acute pain, and menstrual discomfort and pain. the discomfort and swelling relief supplied by this medication helps you perform more of your normal day to day activities. if you are treating a chronic condition such as arthritis. ask your doctor about non-drug remedies and/or using other medications to take care of your pain. see warning section also. this drug functions by blocking the enzyme within your body that makes prostaglandins. reducing prostaglandins helps to reduce pain and swelling. take this medicine with a complete glass of drinking water (8 ounces or 240 milliliters) unless your physician directs you otherwise. do not lay down for 10 moments after taking this medication. for several conditions (such as for example arthritis), it might take up to fourteen days of taking this drug regularly before you get the entire benefit. in case you are taking this medication on an "as needed" basis (not on a normal schedule), understand that pain medications function best if they're used as the 1st signs of pain occur. in the event that you wait before pain has worsened, the medication might not work as well. before taking celecoxib, inform your pharmacist or general practitioner if you are allergic to it; or to aspirin. additional nsaids (such as ibuprofen ), various other cox-2 inhibitors; or in case you have any other allergies. the product might contain inactive elements, which can cause allergies or other problems. speak to your pharmacist for additional information. before using this medication, tell your pharmacist or doctor your health background, especially of: asthma (including a brief history of worsening breathing after taking aspirin or other nsaids), liver disease, stomach/intestine/esophagus problems (such as for example bleeding, ulcers, recurring heartburn), cardiovascular disease (such as angina, coronary attack), high blood circulation pressure, stroke, blood disorders (such as for example anemia, bleeding/clotting problems), growths in the nose (nasal polyps). kidney problems can occur with the usage of nsaid medications sometimes, including celecoxib. problems will occur in case you are dehydrated, have heart kidney or failing disease, are a mature adult, or invest the certain medications (see also drug interactions section). drink lots of liquids as directed by your doctor to avoid dehydration and tell your physician right away for those who have any unusual switch in the quantity of urine. this medicine might cause stomach bleeding. daily utilization of tobacco and alcohol, when coupled with this medicine especially, may boost your risk for belly bleeding. limit smoking and alcohol. check with your pharmacist or doctor to learn more. celecoxib (celebrex) is a nonsteroidal anti-inflammatory drug (nsaid) found in the treating osteoarthritis, rheumatoid arthritis, acute agony, painful menstruation and menstrual symptoms, and also to reduce amounts of colon and rectum polyps in patients with familial adenomatous polyposis. it really is marketed by pfizer beneath the brand name celebrex. in some national countries, it is top quality celebra. celecoxib is available by prescription in capsule form. the system of action of celecoxib is thought to be because of inhibition of prostaglandin synthesis. unlike many nsaids, which inhibit both types of cyclooxygenases (cox-1 and cox-2), celecoxib is a selective non-competitive inhibitor of cyclooxygenase-2 (cox-2) enzyme. it binds using its polar sulfonamide part chain to a hydrophilic aspect pocket region near to the energetic cox-2 binding site. both cox-1 and cox-2 catalyze the transformation of arachidonic acid to prostaglandin (pg) h2, the precursor of thromboxane and pgs. good absorbed in the gastrointestinal tract. whenever a single dose of 200 mg is certainly given to healthy topics, peak plasma levels happen 3 hours after an oral dosage. the peak plasma level is normally 705 ng/ml. absolute bioavailability research have not been carried out. when multiple doses receive, steady-state is usually reached on or before day time 5. when used with a higher fat food, peak plasma amounts are delayed for approximately one to two 2 hours with an upsurge in total absorption (auc) of 10% to 20%. do not consume alcohol even though taking celecoxib. alcoholic beverages can increase the threat of stomach bleeding due to celecoxib. usually do not use any additional over-the-counter cold, allergy, or pain medication without asking your doctor or pharmacist first. many pain medicines obtainable over-the-counter contain aspirin or various other medicines comparable to celecoxib. if you take certain products together you may take too much of this type of medication accidentally. common conditions that celebrex may deal with include: osteoarthritis. joint stiffness, discomfort, and swelling-specifically following inactivity-are r

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